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Anorexia May Be Caused by Brain Chemistry

A study of 200 people—mostly females aged twelve to twenty-five—has radically changed the way doctors think about anorexia. While previous research on the disease has stressed cultural and familial causes of the disease, researchers have now determined that anorexia may be closely related to brain chemistry:

“They found that about 70% of the patients had suffered damage to their neurotransmitters, which help brain cells communicate with each other, had undergone subtle changes in the structure of their brains, or both.”

This finding helps to clarify a long confusion about the risk factors involved in developing anorexia, since all women are exposed to pop culture’s thin obsession, but only about four women in every thousand develop anorexia.

Researchers hope that it may be possible to treat the disease with drugs that work like antidepressants by altering brain chemistry—and to offer parents some peace of mind that their children’s eating disorders are not their fault. According to Susan Ringwood, who runs a leading charity for people suffering from eating disorders, “Parents always blame themselves when their child develops an eating disorder. But what we are learning more and more from research in this area is that some people are very vulnerable to anorexia and that is down to genetic factors and brain chemistry, and not them trying to look like celebrity models or suffering a major traumatic event early in their lives.”

Jezebel writer Hortense is certainly not the only anorexia sufferer who welcomes the news that anorexia can affect anyone, and does not necessarily say anything about one’s childhood or obsession with appearance.

Nevertheless, just as people who are prone to depression are more likely to actually become depressed when certain stress factors are present in their lives, parents and society still have a responsibility to encourage all children to have positive relationships with their bodies—a responsibility that society clearly continues to shirk.

Eventually, it may be possible to test children as young as eight to determine whether they have the anorexia-prone brain abnormality. Would you get your kids screened?

Photo: Jezebel


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Comments

 

jan said:

I'm having trouble finding the actual journal article of this study.  I found the abstract (www3.interscience.wiley.com/.../abstract), but it doesn't show their raw data or explain exactly what the cortical changes were.  It does, however, clarify that the subjects were all anorexia patients at the time of the study.  This is important because any disease (especially psychological disease) usually has an effect on the neuronal structure of the brain.  Networks, neuron birth and death, and links between cortical and sub-cortical structures are plastic, meaning they can be changed through life experience or pathology.  So the anorexia could have caused the changes in the brain structure, rather than the abnormal brain structure causing the anorexia.  I don't know if the researchers controlled the study to make sure this was causation in this direction, but from what I could find their data shows correlation and it's impossible to see which phenomenon was causative.

March 30, 2009 8:21 PM
 

Bunny said:

Yeah, I'd put more faith in this if anorexia were as common a hundred years ago as it is now, before fashion turned ultra-skinny. Yes, I'm sure starving yourself changes your brain, and I'm sure some people are more vulnerable to cultural pressures than others, and that vulnerability may be genetic - but it STARTS with the cultural pressures.

March 31, 2009 2:23 PM
 

leahsmom said:

I know that a lot of treatment for anorexia has moved away from the theory that it's the fault of the patient's family members and towards the idea that it's a disease - like any other disease, one that shouldn't cause blame to be placed on the shoulders of the family.  I'd be excited to see science in support of this, as, anecdotally, the assumption that the parents are at fault is very damaging (often especially to mothers - just like schizophrenia used to be blamed on mothers, and many other illnesses) - though Jan raises excellent points about the study itself.

March 31, 2009 2:27 PM
 

schlockdoc said:

The findings of changes in "neurotransmitters" or in "brain structure"in anorexics mean zilch-zip-zero-nada for the underlying causes or vulnerabilities towards anorexia.

a) We don't know whether the changes predate or postdate the development of the disease,

but the real crux of the issue is

b) *ANY* psychopathology is *NECESSARILY* accompanied by changes in brain chemistry and structure, because *ALL* thoughts, feelings, and experiences are accompanied by changes in brain chemistry and structure.

Whenever a mouse learns something there is an observable, measurable change in its brain structure and chemistry:

www.ncbi.nlm.nih.gov/.../17012063

The better our instruments get, the better able we are to detect subtle changes in brain structure.  Eventually we should be able to measure the chemical and physical changes that occur with ordinary daily activities, like crying when you are hurt.

No doubt kids who are more prone to crying will show differences in brain chemistry and structure than kids who are less prone.  Does that mean that fussiness involves "damage to the neurotransmitters"?  Should we screen our kids to find out if they have fussiness-prone brains?

For some reason the media insists on this simplistic worldview where everything is either biological or psychological.  Those are just two faces of the same coin.

April 4, 2009 8:45 PM

About Hannah Tennant-Moore

Hannah Tennant-Moore is a Brooklyn-based freelance writer whose work has appeared or is forthcoming in Best Buddhist Writing (2008); The Sun; Guantanamo: Inside the Prison, Outside the Law; Tricycle; Turning Wheel (as the winner of the Young Writers Award); and elsewhere.

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