Taking ibuprofen or other similar pain killers early in pregnancy can more than double the risk of miscarriage, new research shows.
A paper, published in the Canadian Medical Association Journal, found that non-steroidal anti-inflammatory drugs (NSAIDs such as Advil and Motrin) taken within the first 20 weeks of pregnancy increased miscarriage risk. Experts are advising women to avoid ibuprofen if they’re trying to get pregnant or are newly pregnant and opt, instead, for acetaminophen (Tylenol).
“The use of non-aspirin NSAIDs during early pregnancy is associated with statistically significant risk (2.4-fold increase) of having a spontaneous abortion,” said Dr. Anick Berard, a lead author of the study.
From The Guardian: “Researchers examined 4,705 cases of miscarriage, of which 352 (7.5%) had taken a non-aspirin NSAID.The women in the study, aged from 15 to 45, were compared with 47,050 women of a similar age who had not lost a baby during pregnancy, of whom 1,213 (2.6%) had used an NSAID.”
Experts say the risk of miscarriage is still low with NSAIDs but this study is consistent with other research I’ve read about the possible risks of ibuprofen during pregnancy. I think it’s been well established that pregnant women should avoid ibuprofen and other NSAIDs but this study might lead to more emphasis on staying clear of these medications around the time of conception and during the early weeks.