Widely prescribed for morning sickness, but especially hyperemesis gravidarium, this drug has not been approved yet for use in pregnancy women. It was originally created for cancer patients undergoing chemotherapy. However, the U.S. has no approved drugs for use in morning sickness, which leaves prescribing Zofran during pregnancy up to the doctor’s discretion.
Zofran can be prescribed in several different forms; a pill that is taken orally with food or water, a dissolvable pill, an injection, or at even a pump for women completely unable to keep anything down.
The Statens Serum Institute in Copenhagen, Denmark, analyzed 608,385 pregnancies of women; a number who had taken Zofran and a number who had been given a placebo. The results were assuring for so many of us: there are no side effects whatsoever. Zofran did not link to an increased risk of miscarriage, still birth, or birth defects. Zofran was not shown to increase the risk of preterm labor or cause low birth weight.
While the side effects to the mother can be a bit brutal during pregnancy (many of us have raging headaches and the oh-so lovely-constipation), they are nothing compared to what all day vomiting does to your body. After 3 pregnancies where I needed Zofran just to get out of bed or stop vomiting, this pill has become essential to me.
Have you taken Zofran? Did it work for you? Does this study make you feel better about needing to use it prior to it being approved by the FDA for pregnancy?
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